TAP1 and TAP2 polymorphism in coeliac disease.

doi:10.1007/BF00210476

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Article

TAP1 and TAP2 polymorphism in coeliac disease.

Immunogenetics - 1 Jan 1993

Powis S H, Rosenberg W M, Hall M, Mockridge I, Tonks S, Ivinson A, Ciclitira P J, Jewell D P, Lanchbury J S, Bell J I

Abstract excerpt

Coeliac disease is strongly associated with HLA-DQ2, but it is possible that additional major histocompatibility complex genes also confer disease susceptibility. Encoded close to HLA-DQ are two genes, TAP1 and TAP2, whose products are believed to transport antigenic peptides from the cytoplasm i...

Topics

ATP Binding Cassette Transporter, Subfamily B, Member 2
ATP Binding Cassette Transporter, Subfamily B, Member 3
ATP-Binding Cassette Transporters
Alleles
Carrier Proteins
Celiac Disease
Histocompatibility Antigens Class II
Humans
Linkage Disequilibrium
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 8344720
DOI: 10.1007/BF00210476

Genes

TAP1
TAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8344720-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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