Celiac disease among Ashkenazi Jews from Israel. A study of the HLA class II alleles and their associations with disease susceptibility.

doi:10.1016/0198-8859(93)90554-e

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Article

Celiac disease among Ashkenazi Jews from Israel. A study of the HLA class II alleles and their associations with disease susceptibility.

Human immunology - 1 Dec 1993

Tighe M R, Hall M A, Ashkenazi A, Siegler E, Lanchbury J S, Ciclitira P J

Abstract excerpt

The immunogenetics of celiac disease demonstrates a highly significant association with the HLA class II alleles DQA1*0501 DQB1*0201 encoded in either a cis- or trans-configuration. In Northern Europe, these alleles are found in linkage disequilibrium with DRB1*0301 while in Southern Europe an additional secondary association through linkage disequilibrium is seen with the combination DRB1*1101/0701. This study...

Topics

Adolescent
Adult
Aged
Celiac Disease
Child
Child, Preschool
Genetic Predisposition to Disease
Genotype
HLA-D Antigens
HLA-DP Antigens
HLA-DQ Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HLA-DR Antigens

Humans

Infant

Israel

Jews

Middle Aged

Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 8138422
DOI: 10.1016/0198-8859(93)90554-e

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8138422-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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