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Article

Analysis of TAP2 polymorphisms in Finnish individuals with type I diabetes.

Human immunology - 1 Jan 2002

Penfornis Alfred, Tuomilehto-Wolf Eva, Faustman Denise L, Hitman Graham A

Abstract excerpt

Type I diabetes mellitus is an immune-mediated disease that is known to be associated and linked with genes in the human leukocyte antigen (HLA) region on chromome 6. Functionally, HLA class I antigen presentation may be deranged in type I diabetes. The TAP1 and TAP2 transporters, which mediate the translocation of antigenic peptides into the endoplasmic reticulum and whose genes are located in the HLA class II...

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Source

Identifiers

PMID: 11916171
DOI: 10.1016/s0198-8859(01)00365-2

Genes

TAP2
TAP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Analysis of TAP2 polymorphisms in Finnish individuals with type I diabetes.PMID 11916171Read ↗

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