Pemphigus vulgaris is associated with the transporter associated with antigen processing (TAP) system.

doi:10.1016/j.humimm.2005.11.004

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Article

Pemphigus vulgaris is associated with the transporter associated with antigen processing (TAP) system.

Human immunology - 1 Dec 2005

Slomov Elena, Loewenthal Ron, Korostishevsky Michael, Goldberg Ilan, Brenner Sarah, Gazit Ephraim

Abstract excerpt

Pemphigus vulgaris (PV) is a human leukocute antigen (HLA) class II-associated autoimmune disease of the skin of unknown etiology. We recently described the association of pemphigus vulgaris with two clusters of microsatellite loci within the major histocompatibility complex region. One cluster includes the microsatellite marker TAP1CA, located in proximity to the transporter associated with antigen processing...

Topics

ATP Binding Cassette Transporter, Subfamily B, Member 3
ATP-Binding Cassette Transporters
Case-Control Studies
Gene Frequency
Genetic Predisposition to Disease
HLA Antigens
Haplotypes
Histocompatibility Antigens Class I
Humans
Israel
Jews
Linkage Disequilibrium
Pemphigus

Source

Open in PubMed

Identifiers

PMID: 16690408
DOI: 10.1016/j.humimm.2005.11.004

Genes

TAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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Polymorphism, Single Nucleotide