Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Suppression of tumorigenicity in human teratocarcinoma cell line PA-1 by introduction of chromosome 4.

Cancer research - 15 May 1994

McGowan-Jordan I J, Speevak M D, Blakey D, Chevrette M

Abstract excerpt

Teratocarcinomas are tumors that develop spontaneously in the gonads and usually contain a rapidly dividing, undifferentiated stem cell population. Immature ovarian teratocarcinomas are highly malignant with only 30-60% of patients surviving for 2 years after diagnosis. We have used microcell fusion to introduce individually tagged normal human chromosomes into the PA-1 human teratocarcinoma cell line....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Genes, Tumor Suppressor
Share to Karyotyping

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Nude

Share to Phenotype

Share to Transfection

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 8168081

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Suppression of tumorigenicity in human teratocarcinoma cell line PA-1 by introduction of chromosome 4.PMID 8168081Read ↗

The distal region of the long arm of human chromosome 1 carries tumor suppressor activity for a human fibrosarcoma line.Semantic proximity Read ↗

Susceptibility for N-ras-mediated transformation requires loss of tumor suppressor activity.Semantic proximity Read ↗

Suppression of transformed phenotype and tumorigenicity after transfer of chromosome 4 into U251 human glioma cells.Semantic proximity Read ↗

Tumorigenicity in human melanoma cell lines controlled by introduction of human chromosome 6.Semantic proximity Read ↗

Evidence that wild-type TP53, and not genes on either chromosome 1 or 11, controls the tumorigenic phenotype of the human fibrosarcoma HT1080.Semantic proximity Read ↗

Suppression of X-ray-induced chromatid breaks in human tumor cells by introduction of normal chromosome 4.Semantic proximity Read ↗

Cellular oncogenes in human teratocarcinoma cell lines.Semantic proximity Read ↗

Stable expression and cell-specific chromatin structure of human alpha1-antitrypsin cosmid transgenes in rat hepatoma cells.Semantic proximity Read ↗

Inhibition of the mutant p53 gene in transformation assays.Semantic proximity Read ↗

Introduction of normal chromosome 3p modulates the tumorigenicity of a human renal cell carcinoma cell line YCR.Semantic proximity Read ↗

Inserting chromosome 18 into pancreatic cancer cells switches them to a dormant metastatic phenotype.Semantic proximity Read ↗

Suppression of tumorigenicity of human prostate cancer cells by introduction of human chromosome del(12)(q13).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.