Introduction of normal chromosome 3p modulates the tumorigenicity of a human renal cell carcinoma cell line YCR.

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Article

Introduction of normal chromosome 3p modulates the tumorigenicity of a human renal cell carcinoma cell line YCR.

Oncogene - 1 Feb 1990

Shimizu M, Yokota J, Mori N, Shuin T, Shinoda M, Terada M, Oshimura M

Abstract excerpt

It has been suggested that loss and/or mutational inactivation of a gene or genes on the short arm of chromosome 3 (3p) may play a crucial role in the development of human renal cell carcinoma (RCC). If it is correct, the normal allele may carry suppressor activity for a tumor-associated phenotyp...

Topics

Animals
Carcinoma, Renal Cell
Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 3
Genotype
Humans
Kidney Neoplasms
Mice
Polymorphism, Restriction Fragment Length
Suppression, Genetic
Transfection
Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 1969617

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1969617-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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