Article
Picornaviral 3C cysteine proteinases have a fold similar to chymotrypsin-like serine proteinases.
Nature - 5 May 1994
Allaire M, Chernaia M M, Malcolm B A, James M N
Abstract excerpt
The picornavirus family includes several pathogens such as poliovirus, rhinovirus (the major cause of the common cold), hepatitis A virus and the foot-and-mouth disease virus. Picornaviral proteins are expressed by direct translation of the genomic RNA into a single, large polyprotein precursor....
Topics
- 3C Viral Proteases
- Amino Acid Sequence
- Chymotrypsin
- Computer Graphics
- Crystallography, X-Ray
- Cysteine Endopeptidases
- Hepatovirus
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Protein Folding
- Viral Proteins