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Picornavirus 3C Proteins Intervene in Host Cell Processes through Proteolysis and Interactions with RNA

12 Dec 2023

Abstract excerpt

family comprises a large group of non-enveloped viruses with enormous impact on human and animal health. The picornaviral genome contains one open reading frame encoding a single polyprotein that can be processed by viral proteases. The picornaviral 3C proteases share similar three-dimensional structures and play a significant role in the viral life cycle and virus-host interactions. Picornaviral 3C proteins also...

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PMID: 38140654
DOI: 10.3390/v15122413

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