Article
Lack of association of the insulin gene region with type 1 (insulin-dependent) diabetes mellitus in Japanese subjects.
Diabetologia - 1 Feb 1994
Matsumoto C, Awata T, Iwamoto Y, Kuzuya T, Saito T, Kanazawa Y
Abstract excerpt
Although the insulin gene region is implicated in susceptibility to Type 1 (insulin-dependent) diabetes mellitus in Caucasians, significance of this region to Type 1 diabetes in Japanese remains unclear because the class 1 alleles (shorter insertion) of the variable number of tandem repeat in the 5' region of the insulin gene are predominant in both diabetic and non-diabetic subjects. The 5' insulin gene...
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