Article
Lack of association of the insulin gene region with type 1 (insulin-dependent) diabetes mellitus in Japanese subjects.
Diabetologia - 1 Feb 1994
Matsumoto C, Awata T, Iwamoto Y, Kuzuya T, Saito T, Kanazawa Y
Abstract excerpt
Although the insulin gene region is implicated in susceptibility to Type 1 (insulin-dependent) diabetes mellitus in Caucasians, significance of this region to Type 1 diabetes in Japanese remains unclear because the class 1 alleles (shorter insertion) of the variable number of tandem repeat in the...
Topics
- Age of Onset
- Alleles
- Base Sequence
- DNA Primers
- Deoxyribonucleases, Type II Site-Specific
- Diabetes Mellitus, Type 1
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Insulin
- Japan
- Male
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Reference Values
- Repetitive Sequences, Nucleic Acid
