Article
[Relationship between the mutation of insulin receptor substrate-1 gene 3'untranslated region and type 2 diabetes in the Chinese].
Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University - 28 Feb 2003
Chen Shu-hua, Gu Ya-peng, Zeng Wei-min
Abstract excerpt
OBJECTIVE: To study the relationship between the mutation of the insulin receptor substrate-1 (IRS-1) gene 3'untranslated region and Type 2 diabetes in the Chinese. METHODS: Samples were obtained from 120 Chinese patients with Type 2 diabetes and 120 control subjects. The 3'untranslated region sequence of IRS-1 gene was screened by the polymerase chain reaction (PCR)-single strand conformation polymorphism (SSCP)...
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