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Article

Absence of association of TAP and LMP genes with type 1 (insulin-dependent) diabetes mellitus.

Life sciences - 1 Jan 1994

Kawaguchi Y, Ikegami H, Fukuda M, Takekawa K, Fujioka Y, Fujisawa T, Ueda H, Ogihara T

Abstract excerpt

Although one of the major genes which cause type 1 (insulin-dependent) diabetes mellitus is located in the class II HLA region in humans, its precise location is still unknown. In order to investigate whether TAP (Transporter associated with Antigen Processing) and LMP (Low Molecular Weight Polypeptide) genes, which are located in the class II HLA region, are HLA-linked diabetogenic genes, the association of...

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Source

Identifiers

PMID: 7911550
DOI: 10.1016/0024-3205(94)00713-6

Genes

TAP1
TAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Absence of association of TAP and LMP genes with type 1 (insulin-dependent) diabetes mellitus.PMID 7911550Read ↗

Lack of association of the transporter associated with antigen processing with Japanese insulin-dependent diabetes mellitus.Semantic proximity Read ↗

Susceptibility to type 1 diabetes in the Senegalese population is linked to HLA-DQ and not TAP and LMP genes.Semantic proximity Read ↗

Insulin-dependent diabetes mellitus and the major histocompatibility complex peptide transporters TAP1 and TAP2: no association in a population with a high disease incidence.Semantic proximity Read ↗

Susceptibility to insulin-dependent diabetes mellitus and short cytoplasmic ATP-binding domain TAP2*01 alleles.Semantic proximity Read ↗

Genetic heterogeneity between type 1a and type 1b insulin-dependent diabetes mellitus: HLA class II and TAP gene analysis.Semantic proximity Read ↗

Polymorphisms of TAP1 and TAP2 genes in German patients with type 1 diabetes mellitus.Semantic proximity Read ↗

TAP2 association with insulin-dependent diabetes mellitus is secondary to HLA-DQB1.Semantic proximity Read ↗

Effect of human leukocyte antigen class II genes on insulin deficiency in slow-onset type 1 diabetes in the Japanese population.Semantic proximity Read ↗

Family study of linkage disequilibrium between TAP2 transporter and HLA class II genes. Absence of TAP2 contribution to association with insulin-dependent diabetes mellitus.Semantic proximity Read ↗

Major histocompatibility complex-encoded antigen processing gene polymorphism in IDDM.Semantic proximity Read ↗

TAP1 alleles in insulin-dependent diabetes mellitus: a newly defined centromeric boundary of disease susceptibility.Semantic proximity Read ↗

TAP1 and TAP2 transporter genes and predisposition to insulin dependent diabetes mellitus.Semantic proximity Read ↗

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