IDDM susceptibility associated with polymorphisms in the insulin gene region. A study of blacks, Caucasians and orientals.

doi:10.1007/BF00404330

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

IDDM susceptibility associated with polymorphisms in the insulin gene region. A study of blacks, Caucasians and orientals.

Diabetologia - 1 Aug 1994

Undlien D E, Hamaguchi K, Kimura A, Tuomilehto-Wolf E, Swai A B, McLarty D G, Tuomilehto J, Thorsby E, Rønningen K S

Abstract excerpt

Previous studies have suggested an association between polymorphisms in the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Most of the studies so far have been performed in Caucasoid populations. We have investigated 418 random IDDM patients and 422 healthy control subjects from three different ethnic groups; Tanzanian blacks, Norwegian Caucasians and Japanese orientals. Our data suggest that...

Topics

Adult
Asian People
Black People
Diabetes Mellitus, Type 1
Genetic Predisposition to Disease
Genotype
HLA-DR Antigens
Humans
Insulin
Japan
Norway

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Predictive Value of Tests

Random Allocation

Reference Values

Risk Factors

Tanzania

White People

Source

Open in PubMed

Identifiers

PMID: 7988775
DOI: 10.1007/BF00404330

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7988775-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IDDM susceptibility associated with polymorphisms in the insulin gene region. A study of blacks, Caucasians and orientals.PMID 7988775Read ↗

The insulin gene region and susceptibility to insulin-dependent diabetes mellitus in four races; new insights from Afro-Caribbean race-specific haplotypes.Semantic proximity Read ↗

Insulin gene region-encoded susceptibility to IDDM maps upstream of the insulin gene.Semantic proximity Read ↗

Insulin gene region contributes to genetic susceptibility to, but may not to low incidence of, insulin-dependent diabetes mellitus in Japanese.Semantic proximity Read ↗

Non-HLA region genes in insulin dependent diabetes mellitus.Semantic proximity Read ↗

Genes for insulin-dependent diabetes mellitus (IDDM) in the major histocompatibility complex (MHC) of African-Americans.Semantic proximity Read ↗

Diabetes susceptibility at IDDM2 cannot be positively mapped to the VNTR locus of the insulin gene.Semantic proximity Read ↗

Additive susceptibility to insulin-dependent diabetes conferred by HLA-DQB1 and insulin genes.Semantic proximity Read ↗

HLA-DQA and DQB alleles contribute to susceptibility to insulin-dependent diabetes mellitus.Semantic proximity Read ↗

Lack of association of the insulin gene region with type 1 (insulin-dependent) diabetes mellitus in Japanese subjects.Semantic proximity Read ↗

[Non-MHC susceptibility genes in Japanese subjects with insulin-dependent diabetes mellitus (IDDM)].Semantic proximity Read ↗

Genetic markers for insulin-dependent diabetes mellitus in Japanese.Semantic proximity Read ↗

5' insulin gene polymorphism confers risk to IDDM independently of HLA class II susceptibility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.