Article
Insulin gene region contributes to genetic susceptibility to, but may not to low incidence of, insulin-dependent diabetes mellitus in Japanese.
Biochemical and biophysical research communications - 7 Apr 1997
Kawaguchi Y, Ikegami H, Shen G Q, Nakagawa Y, Fujisawa T, Hamada Y, Ueda H, Fu J, Uchigata Y, Kitagawa Y, Omori Y, Shima K, Ogihara T
Abstract excerpt
In the Caucasian population, it has been demonstrated that the insulin gene (INS) region contains the insulin-dependent diabetes mellitus locus (IDDM2). In the Japanese population, however, there has been no report demonstrating the contribution of IDDM2 to the pathogenesis of IDDM. We conducted an association study of IDDM in a large number of Japanese subjects with multiple polymorphisms in INS region. We found...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.