Article
Insulin gene region contributes to genetic susceptibility to, but may not to low incidence of, insulin-dependent diabetes mellitus in Japanese.
Biochemical and biophysical research communications - 7 Apr 1997
Kawaguchi Y, Ikegami H, Shen G Q, Nakagawa Y, Fujisawa T, Hamada Y, Ueda H, Fu J, Uchigata Y, Kitagawa Y, Omori Y, Shima K, Ogihara T
Abstract excerpt
In the Caucasian population, it has been demonstrated that the insulin gene (INS) region contains the insulin-dependent diabetes mellitus locus (IDDM2). In the Japanese population, however, there has been no report demonstrating the contribution of IDDM2 to the pathogenesis of IDDM. We conducted...
Topics
- DNA, Satellite
- Diabetes Mellitus, Type 1
- Genetic Predisposition to Disease
- Humans
- Insulin
- Japan
- Meta-Analysis as Topic
- Minisatellite Repeats
- Polymorphism, Genetic