[Non-MHC susceptibility genes in Japanese subjects with insulin-dependent diabetes mellitus (IDDM)].

Article

[Non-MHC susceptibility genes in Japanese subjects with insulin-dependent diabetes mellitus (IDDM)].

Nihon rinsho. Japanese journal of clinical medicine - 1 Oct 1994

Matsumoto C, Awata T

Abstract excerpt

Genetic factors clearly contribute to the development of autoimmune destruction of pancreatic beta cell in IDDM. The HLA class II genes have an important role in the pathogenesis of Japanese IDDM as they do in Caucasians. Particular HLA class II alleles and haplotypes contribute to the IDDM susce...

Topics

Asian People
Diabetes Mellitus, Type 1
Genetic Predisposition to Disease
Haplotypes
Histocompatibility Antigens Class II
Humans
Insulin
Japan
Major Histocompatibility Complex
Polymorphism, Genetic

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