Restriction fragment length polymorphisms near the islet amyloid polypeptide gene in Japanese subjects.

doi:10.1016/0168-8227(92)90001-8

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Article

Restriction fragment length polymorphisms near the islet amyloid polypeptide gene in Japanese subjects.

Diabetes research and clinical practice - 1 Nov 1992

Ohagi S, Ekawa K, Sanke T, Nishi M, Nanjo K

Abstract excerpt

Two restriction fragment length polymorphisms (RFLPs) near the human islet amyloid polypeptide (IAPP) gene were examined in 50 Japanese patients with non-insulin-independent diabetes mellitus (NIDDM) and 54 non-diabetic controls. RFLPs were identified with the enzymes PvuII (A1 = 21 kb and A2 = 18 kb) and BglII (B1 = 9 kb and B2 = 7 kb). These RFLPs were in complete linkage disequilibrium with A1 which was in...

Topics

Adult
Aged
Alleles
Amyloid
Bacterial Proteins
Blotting, Southern
DNA
Deoxyribonucleases, Type II Site-Specific
Diabetes Mellitus, Type 2
Female
Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genotype

Humans

Islet Amyloid Polypeptide

Japan

Linkage Disequilibrium

Lymphocytes

Male

Source

Open in PubMed

Identifiers

PMID: 1362147
DOI: 10.1016/0168-8227(92)90001-8

Genes

IAPP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1362147-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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