Article
Lack of association of T cell receptor beta-chain constant region polymorphism with insulin-dependent diabetes mellitus in Finland.
Clinical and experimental immunology - 1 Sept 1990
Reijonen H, Silvennoinen-Kassinen S, Ilonen J, Knip M
Abstract excerpt
Allelic polymorphism in the T cell receptor constant beta-chain gene region has been reported to be associated with autoimmune diseases, including insulin-dependent diabetes mellitus (IDDM). The present analysis of 164 children and adolescents with IDDM and 193 controls for BqlII polymorphism usi...
Topics
- Adolescent
- Alleles
- Child
- DNA Probes
- Diabetes Mellitus, Type 1
- Disease Susceptibility
- Finland
- Gene Frequency
- Genotype
- HLA-DR Antigens
- Humans
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
- Receptors, Antigen, T-Cell
- Receptors, Antigen, T-Cell, alpha-beta
