Analysis of p53 in human cutaneous melanoma cell lines.

Article

Analysis of p53 in human cutaneous melanoma cell lines.

Oncogene - 1 May 1994

Montano X, Shamsher M, Whitehead P, Dawson K, Newton J

Abstract excerpt

Mutations in the p53 tumour suppressor gene have been detected in a variety of human malignancies. Mutations have been found predominantly in conserved regions two to five. Our aim was to analyse p53 at the protein and DNA level in seven melanoma cell lines of cutaneous origin (HMB-2, DX3, LT5.1,...

Topics

Cell Nucleus
Genes, p53
Humans
Melanoma
Mutation
Sequence Analysis, DNA
Skin Neoplasms
Tumor Cells, Cultured
Tumor Suppressor Protein p53

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