Article
Analysis of p53 in human cutaneous melanoma cell lines.
Oncogene - 1 May 1994
Montano X, Shamsher M, Whitehead P, Dawson K, Newton J
Abstract excerpt
Mutations in the p53 tumour suppressor gene have been detected in a variety of human malignancies. Mutations have been found predominantly in conserved regions two to five. Our aim was to analyse p53 at the protein and DNA level in seven melanoma cell lines of cutaneous origin (HMB-2, DX3, LT5.1, MJM, SK23, A375P and A375M), including two parental/metastatic derivatives (A375P and A375M; DX3 and LT5.1). By...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
