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Article

Comprehensive analysis of the p53 status in mucosal and cutaneous melanomas.

International journal of cancer - 1 Feb 2006

Gwosdz Christian, Scheckenbach Kathrin, Lieven Oliver, Reifenberger Julia, Knopf Andreas, Bier Henning, Balz Vera

Abstract excerpt

The abrogation of the function of the "gatekeeper of the genome", p53, is the most prevalent molecular alteration in solid human tumors. Regarding melanomas the involvement of p53 alterations is discussed controversially to date. In order to evaluate the status of p53 in detail, primary tumors and metastases of 63 sporadic cutaneous (CM) and mucosal (MuM) melanomas were examined by immunohistochemistry and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16094622
DOI: 10.1002/ijc.21366

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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