Article
Molecular mechanisms of tumor progression in chronic myeloproliferative disorders.
Leukemia - 1 Apr 1994
Gaidano G, Guerrasio A, Serra A, Rege-Cambrin G, Saglio G
Abstract excerpt
We have investigated the involvement of tumor suppressor genes (p53 and RB1) and dominantly acting oncogenes (Ras family genes) in BCR/ABL positive and negative chronic myeloproliferative disorders (CMPD) at different stages of the disease, including 26 cases of BCR/ABL+ chronic myeloid leukemia...
Topics
- Chronic Disease
- Fusion Proteins, bcr-abl
- Genes, Retinoblastoma
- Genes, p53
- Genes, ras
- Humans
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive
- Mutation
- Myeloproliferative Disorders