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Molecular events in chronic myeloid leukemia progression.

Leukemia - 1 Apr 1997

Guerrasio A, Serra A, Gottardi E, Cilloni D, Vischia F, Parvis G, Cilli V, Saglio G

Abstract excerpt

Chronic myelogenous leukemia presents two distinct clinical phases: the chronic phase is characterised by a marked expansion of the myeloid compartment which still retains a normal differentiative capacity, whereas a differentiation block is the clinical hallmark of the acute transformation. The molecular mechanism underlying the CML progression are still poorly understood. The occurrence of additional molecular...

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PMID: 9209443

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BCR

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