Long-term persistence of AZT-resistance mutations in the plasma HIV-1 of patients removed from AZT therapy.

Article

Long-term persistence of AZT-resistance mutations in the plasma HIV-1 of patients removed from AZT therapy.

Leukemia - 1 Apr 1994

Smith M S, Koerber K L, Pagano J S

Abstract excerpt

Zidovudine (3'-azido-2',3'-dideoxythymidine) resistant isolates of human immunodeficiency virus type I (HIV-1) were previously demonstrated in zidovudine-treated AIDS patients. The genetic linkage of multiple mutations characteristic of zidovudine-resistance as well as dideoxyinosine-resistance w...

Topics

Acquired Immunodeficiency Syndrome
Drug Resistance
HIV-1
Humans
Mutation
Time Factors
Zidovudine

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