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Article

Dynamic changes in HIV-1 quasispecies from azidothymidine (AZT)-treated patients.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jul 1992

Wahlberg J, Albert J, Lundeberg J, Cox S, Wahren B, Uhlén M

Abstract excerpt

The emergence of azidothymidine (AZT)-resistant human immunodeficiency virus (HIV) variants in clinical samples was studied by a direct genomic sequencing method. Sequential lymphocyte samples from four patients, who had been treated with AZT for up to 27 months, were shown to gradually accumulate multiple nucleotide changes, some of which are known to be associated with AZT resistance. Several samples were shown...

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Source

Identifiers

PMID: 1634047
DOI: 10.1096/fasebj.6.10.1634047

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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