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Article

Persistence of azidothymidine-resistant human immunodeficiency virus type 1 RNA genotypes in posttreatment sera.

Journal of virology - 1 Sept 1992

Albert J, Wahlberg J, Lundeberg J, Cox S, Sandström E, Wahren B, Uhlén M

Abstract excerpt

The rate of reversion from azidothymidine (zidovudine; AZT) resistance was studied by direct sequencing of human immunodeficiency virus type 1 (HIV-1) virion RNA in sera from four patients who discontinued long-term treatment. Before cessation of treatment, all four patients harbored HIV-1 with multiple mutations reported to confer AZT resistance. In three patients, slow reversions of these mutations starting...

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Identifiers

PMID: 1380098
DOI: 10.1128/JVI.66.9.5627-5630.1992
PMCID: PMC289127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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