Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A protease activation mutant, MVCES1, as a safe and potent live vaccine derived from currently prevailing Sendai virus.

Journal of virology - 1 May 1994

Wang X L, Itoh M, Hotta H, Homma M

Abstract excerpt

Sendai virus fresh isolates were shown to be antigenically different from the prototype Fushimi strain that had long been passaged in embryonated chicken eggs. Phylogenetic analysis of the hemagglutinin-neuraminidase genes also revealed the difference between these two virus groups. Both trypsin-resistant and elastase-sensitive mutations were additionally introduced to an LLC-MK2-cell-adapted and attenuated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Endopeptidases
Share to Mice

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred BALB C

Share to Molecular Sequence Data

Share to Mutation

Share to Sequence Homology, Amino Acid

Share to Vaccines, Attenuated

Source

Open in PubMed Open full text

Identifiers

PMID: 8151795
DOI: 10.1128/JVI.68.5.3369-3373.1994
PMCID: PMC236828

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A protease activation mutant, MVCES1, as a safe and potent live vaccine derived from currently prevailing Sendai virus.PMID 8151795Read ↗

Evaluation of a protease activation mutant of Sendai virus as a potent live vaccine.Semantic proximity Read ↗

Isolation of an avirulent mutant of Sendai virus with two amino acid mutations from a highly virulent field strain through adaptation to LLC-MK2 cells.Semantic proximity Read ↗

Pneumopathogenicity of a Sendai virus protease-activation mutant, TCs, which is sensitive to trypsin and chymotrypsin.Semantic proximity Read ↗

The potential of a protease activation mutant of a highly pathogenic avian influenza virus for a pandemic live vaccine.Semantic proximity Read ↗

Isolation of a wild type measles virus classified as genotype H1 in osaka city.Semantic proximity Read ↗

Live-attenuated influenza virus vaccine strain with an engineered temperature-sensitive and genetically stable viral polymerase variant.Semantic proximity Read ↗

Characterization of live influenza vaccine donor strain derived from cold-adaptation of X-31 virus.Semantic proximity Read ↗

Influenza B virus with modified hemagglutinin cleavage site as a novel attenuated live vaccine.Semantic proximity Read ↗

A new approach to an influenza live vaccine: modification of the cleavage site of hemagglutinin.Semantic proximity Read ↗

A field isolate of Sendai virus: its high virulence to mice and genetic divergence form prototype strains.Semantic proximity Read ↗

Genetic analysis of attenuation markers of cold-adapted X-31 influenza live vaccine donor strain.Semantic proximity Read ↗

Determinants of organ tropism of Sendai virus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.