A protease activation mutant, MVCES1, as a safe and potent live vaccine derived from currently prevailing Sendai virus.

doi:10.1128/JVI.68.5.3369-3373.1994

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Article

A protease activation mutant, MVCES1, as a safe and potent live vaccine derived from currently prevailing Sendai virus.

Journal of virology - 1 May 1994

Wang X L, Itoh M, Hotta H, Homma M

Abstract excerpt

Sendai virus fresh isolates were shown to be antigenically different from the prototype Fushimi strain that had long been passaged in embryonated chicken eggs. Phylogenetic analysis of the hemagglutinin-neuraminidase genes also revealed the difference between these two virus groups. Both trypsin-...

Topics

Amino Acid Sequence
Animals
Endopeptidases
Hemagglutinins, Viral
Mice
Mice, Inbred BALB C
Molecular Sequence Data
Mutation
Parainfluenza Virus 1, Human
Paramyxoviridae Infections
Safety
Sequence Homology, Amino Acid
Vaccination
Vaccines, Attenuated
Viral Fusion Proteins
Viral Vaccines

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Identifiers

PMID: 8151795
DOI: 10.1128/JVI.68.5.3369-3373.1994
PMCID: PMC236828

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8151795-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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