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Article

Evaluation of a protease activation mutant of Sendai virus as a potent live vaccine.

Veterinary microbiology - 1 Jan 1992

Maru M, Haraguchi M, Sato K, Hotta H, Homma M

Abstract excerpt

A protease activation mutant of Sendai virus, TR-5, was investigated as a candidate for a live vaccine. Vaccination with TR-5 which had been activated by chymotrypsin beforehand (active TR-5) elicited protective immunity against otherwise lethal challenge infection with wild-type Sendai virus in DBA/2, C3H and ICR strains of mice. Less of the active TR-5 was required to confer protection on mice compared with an...

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Identifiers

PMID: 1311131
DOI: 10.1016/0378-1135(92)90089-c

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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