Article
A field isolate of Sendai virus: its high virulence to mice and genetic divergence form prototype strains.
Archives of virology - 1 Jan 1994
Sakaguchi T, Kiyotani K, Sakaki M, Fujii Y, Yoshida T
Abstract excerpt
A field isolate of Sendai virus, the Hamamatsu strain, was far more virulent in mice than the prototype Z strain. The Hamamatsu strain replicated more efficiently in the mouse lung than the Z strain, causing deteriorating lung lesions. Nucleotide sequence analysis of the HN, F and M genes reveale...
Topics
- Animals
- Base Sequence
- DNA Primers
- Genetic Variation
- Lung
- Male
- Mice
- Mice, Inbred ICR
- Molecular Sequence Data
- Parainfluenza Virus 1, Human
- Paramyxoviridae Infections
- Sequence Homology, Amino Acid
- Sequence Homology, Nucleic Acid
- Species Specificity
- Viral Proteins
- Virulence
- Virus Replication