Article
Determinants of organ tropism of Sendai virus.
Frontiers in bioscience : a journal and virtual library - 1 Dec 1997
Tashiro M, Seto J T
Abstract excerpt
Wild-type Sendai virus is exclusively pneumotropic in mice. Protease activation mutants, ts-f1 and F1-R, were isolated from persistently infected tissue culture cells. Additional mutants were isolated from wild-type Sendai virus with phenotypes similar to the pantropic mutant, F1-R. The genome of...
Topics
- Animals
- Bronchi
- Mice
- Mutation
- Organ Specificity
- Sendai virus
- Serine Endopeptidases
- Tryptases
- Viral Fusion Proteins
- Viral Matrix Proteins