Pneumopathogenicity of a Sendai virus protease-activation mutant, TCs, which is sensitive to trypsin and chymotrypsin.

doi:10.1128/JVI.64.11.5660-5664.1990

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Article

Pneumopathogenicity of a Sendai virus protease-activation mutant, TCs, which is sensitive to trypsin and chymotrypsin.

Journal of virology - 1 Nov 1990

Itoh M, Ming T D, Hayashi T, Mochizuki Y, Homma M

Abstract excerpt

A protease-activation mutant of Sendai virus, TCs, was isolated from a trypsin-resistant mutant, TR-5. TCs was activated in vitro by both trypsin and chymotrypsin. TCs was, however, less sensitive to trypsin and chymotrypsin than were the wild-type virus and TR-5, respectively. F protein of TCs h...

Topics

Amino Acid Sequence
Animals
Base Sequence
Chymotrypsin
Lung
Lung Diseases
Mice
Molecular Sequence Data
Mutation
Parainfluenza Virus 1, Human
Paramyxoviridae Infections
Trypsin
Viral Fusion Proteins
Virus Replication

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