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Article

Simian virus 40 DNA replication correlates with expression of a particular subclass of T antigen in a human glial cell line.

Journal of virology - 1 Aug 1990

Deminie C A, Norkin L C

Abstract excerpt

Immunocytochemistry and in situ hybridization were used to identify simian virus 40 (SV40) large T-antigen expression and viral DNA replication in individual cells of infected semipermissive human cell lines. SV40 infection aborts before T-antigen expression in many cells of each of the human cell lines examined. In all but one of the human cell lines, most of the T-antigen-producing cells replicated viral DNA....

Topics

Animals
Antibodies, Monoclonal
Antigens, Polyomavirus Transforming
Capsid
Cell Line
DNA Probes
DNA Replication
DNA, Viral
Glioma
Humans
Mutation
Nucleic Acid Hybridization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Simian virus 40

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Open in PubMed Open full text

Identifiers

PMID: 2164596
DOI: 10.1128/JVI.64.8.3760-3769.1990
PMCID: PMC249671

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2164596-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Simian virus 40 DNA replication correlates with expression of a particular subclass of T antigen in a human glial cell line.PMID 2164596Read ↗

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