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Article

A simple and rapid technique for the detection of rifampin resistance in Mycobacterium leprae.

International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association - 1 Dec 1993

Honoré N, Perrani E, Telenti A, Grosset J, Cole S T

Abstract excerpt

The rifampin resistance of Mycobacterium leprae is due to missense mutations in the rpoB gene encoding the beta-subunit of the essential enzyme RNA polymerase. A rapid and very simple method has been developed to detect rifampin resistance in small numbers of M. leprae present in biopsies. It involves polymerase chain reaction amplification of a defined region of the rpoB gene followed by single-strand...

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PMID: 8151192

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A simple and rapid technique for the detection of rifampin resistance in Mycobacterium leprae.PMID 8151192Read ↗

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Detection of rifampicin-resistance mutations in Mycobacterium tuberculosis.Semantic proximity Read ↗

Characterization of rifampin-resistance in pathogenic mycobacteria.Semantic proximity Read ↗

Detection of mutations in folp1, rpoB and gyrA genes of M. leprae by PCR- direct sequencing--a rapid tool for screening drug resistance in leprosy.Semantic proximity Read ↗

Rifampicin resistance in Mycobacterium tuberculosis--rapid detection and implications in chemotherapy.Semantic proximity Read ↗

Development and evaluation of a novel multiple-primer PCR amplification refractory mutation system for the rapid detection of mutations conferring rifampicin resistance in codon 425 of the rpoB gene of Mycobacterium leprae.Semantic proximity Read ↗

Rapid detection of rpoB mutations in rifampin resistant M. tuberculosis from sputum samples by denaturing gradient gel electrophoresis.Semantic proximity Read ↗

Use of DNA extracts from Ziehl-Neelsen-stained slides for molecular detection of rifampin resistance and spoligotyping of Mycobacterium tuberculosis.Semantic proximity Read ↗

Mutation at codon 442 in the rpoB gene of Mycobacterium leprae does not confer resistance to rifampicin.Semantic proximity Read ↗

Detection of Rifampin-Resistant <i>Mycobacterium tuberculosis</i> in Sputa by Nested PCR-Linked Single-Strand Conformation Polymorphism and DNA SequencingSemantic proximity Read ↗

Structural Implications of Mutations Conferring Rifampin Resistance in Mycobacterium leprae.Semantic proximity Read ↗

Low-stringency single-specific-primer PCR as a tool for detection of mutations in the rpoB gene of rifampin-resistant Mycobacterium tuberculosis.Semantic proximity Read ↗

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