Detection of rifampicin-resistance mutations in Mycobacterium tuberculosis.

doi:10.1016/0140-6736(93)90417-f

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Article

Detection of rifampicin-resistance mutations in Mycobacterium tuberculosis.

Lancet (London, England) - 13 Mar 1993

Telenti A, Imboden P, Marchesi F, Lowrie D, Cole S, Colston M J, Matter L, Schopfer K, Bodmer T

Abstract excerpt

Control of tuberculosis is threatened by widespread emergence of drug resistance in Mycobacterium tuberculosis. Understanding the molecular basis of resistance might lead to development of novel rapid methods for diagnosing drug resistance. We set out to determine the molecular basis of resistanc...

Topics

Base Sequence
DNA-Directed RNA Polymerases
Drug Resistance, Microbial
Molecular Sequence Data
Mutation
Mycobacterium tuberculosis
Polymerase Chain Reaction
Rifampin

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