Article
Rifampicin resistance in Mycobacterium tuberculosis--rapid detection and implications in chemotherapy.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde - 1 Jan 1996
Pretorius G S, Sirgel F A, Schaaf H S, van Helden P D, Victor T C
Abstract excerpt
OBJECTIVES: Tuberculosis treatment and susceptibility testing are cumbersome, especially in the case of multidrug-resistant (MDR) Mycobacterium tuberculosis. It is known that mutations in the rpoB gene of M. tuberculosis lead to resistance to rifampicin (RMP). In this study, an attempt was made to apply molecular techniques for rapid detection of antibiotic resistance in clinical isolates of M. tuberculosis....
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