Article
Characterization of rifampin-resistance in pathogenic mycobacteria.
Antimicrobial agents and chemotherapy - 1 Oct 1994
Williams D L, Waguespack C, Eisenach K, Crawford J T, Portaels F, Salfinger M, Nolan C M, Abe C, Sticht-Groh V, Gillis T P
Abstract excerpt
The emergence of rifampin-resistant strains of pathogenic mycobacteria has threatened the usefulness of this drug in treating mycobacterial diseases. Critical to the treatment of individuals infected with resistant strains is the rapid identification of these strains directly from clinical specim...
Topics
- Amino Acid Sequence
- Base Sequence
- DNA-Directed RNA Polymerases
- Drug Resistance, Microbial
- Microbial Sensitivity Tests
- Molecular Sequence Data
- Mutation
- Mycobacterium
- Polymerase Chain Reaction
- Rifampin