Article
Use of DNA extracts from Ziehl-Neelsen-stained slides for molecular detection of rifampin resistance and spoligotyping of Mycobacterium tuberculosis.
Journal of clinical microbiology - 1 Mar 2003
Van Der Zanden A G M, Te Koppele-Vije E M, Vijaya Bhanu N, Van Soolingen D, Schouls L M
Abstract excerpt
Multidrug resistance among new cases of tuberculosis (TB) is increasingly becoming a significant problem in countries with a high prevalence of TB and with inadequate therapies for TB. Rifampin resistance is widely used as a marker for multidrug-resistant (MDR) TB; therefore, a new approach to the retrospective measurement of rifampin resistance without the need of a viable culture has been introduced. In many...
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