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Article

Effect of genetic architecture on the power of human linkage studies to resolve the contribution of quantitative trait loci.

Heredity - 1 Feb 1994

Eaves L J

Abstract excerpt

The effect of genetic architecture (linkage relationships, dominance and two forms of non-allelic interaction) on the power of marker studies to detect, locate and analyse the contributions of specific quantitative trait loci (QTLs) to continuous human traits is considered for randomly mating populations in linkage equilibrium under a two-locus model. The expected regression of the within-sibling-pair mean-square...

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PMID: 8150657
DOI: 10.1038/hdy.1994.25

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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