Detection of human genetic linkage: foundations.

doi:10.1006/tpbi.2001.1534

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Article

Detection of human genetic linkage: foundations.

Theoretical population biology - 1 Nov 2001

Thompson E

Abstract excerpt

Starting with the basics of inheritance, recombination, and genetic map distance, we develop the theory of linkage analysis considering data on an individual or on a sib pair, with and without data on parents. We discuss the effects of ascertainment of individuals with certain traits and the effects of allelic associations between a trait and a linked marker locus.

Topics

Alleles
Genetic Linkage
Genetic Variation
Haplotypes
Humans
Models, Genetic
Pedigree
Phenotype
Recombination, Genetic

Source

Open in PubMed

Identifiers

PMID: 11855954
DOI: 10.1006/tpbi.2001.1534

Provenance

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