Article
Detection of human genetic linkage: foundations.
Theoretical population biology - 1 Nov 2001
Thompson E
Abstract excerpt
Starting with the basics of inheritance, recombination, and genetic map distance, we develop the theory of linkage analysis considering data on an individual or on a sib pair, with and without data on parents. We discuss the effects of ascertainment of individuals with certain traits and the effects of allelic associations between a trait and a linked marker locus.
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