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Article

Multipoint analysis of human quantitative genetic variation.

American journal of human genetics - 1 Dec 1990

Goldgar D E

Abstract excerpt

A unique method of partitioning human quantitative genetic variation into effects due to specific chromosomal regions is presented. This method is based on estimating the proportion of genetic material, R, shared identical by descent (IBD) by sibling pairs in a specified chromosomal region, on the basis of their marker genotypes at a set of marker loci spanning the region. The mean and variance of the...

Topics

Chromosomes, Human, Pair 7
Female
Genetic Linkage
Genetic Markers
Genetic Variation
Genotype
Humans
Male
Mathematics
Models, Genetic
Monte Carlo Method
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Recombination, Genetic

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Open in PubMed Open full text

Identifiers

PMID: 2239972
PMCID: PMC1683895

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2239972-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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