Article
The regulatory complex of HLA class I promoters exhibits locus-specific conservation with limited allelic variation.
Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 1994
Cereb N, Yang S Y
Abstract excerpt
The extensive genetic polymorphism of the classical MHC class I molecules provides an important distinguishing feature of the host's immune system. They influence the selection and function of effector cells against tumor and virally infected cells. In these cells, class I molecules are often selectively suppressed. This suppression is locus specific and, in certain cases, allele specific. We analyzed the HLA...
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