Article
Nonrandom allelic variation in the regulatory complex of HLA class I genes.
Human immunology - 1 Sept 1994
Cereb N, Lee S, Maye P, Kong Y, Yang S Y
Abstract excerpt
Recently, we have demonstrated that the HLA class I regulatory complex (CRC) is conserved in a locus-specific manner with limited allelic variation. In this study, we have analyzed the CRC sequences of the alleles that showed variation from a total of 22 well-characterized, HLA-homozygous B-LCLs, using PCR amplification of genomic DNA and direct sequencing. We compared the sequences of these alleles with their...
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