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Article

A common mutation in the hominoid class I A-locus IFN-responsive element results in the loss of enhancer activity.

International immunology - 1 May 1995

Vallejo A N, Allen K S, Pease L R

Abstract excerpt

Despite the observed coordinate expression of HLA-A and -B antigens in somatic tissues, there is growing evidence that the A and B class I genes are differentially regulated at the transcriptional level. Previous studies indicate that this may be related to locus-specific structural differences in certain enhancer elements. We have recently examined the 5' proximal regulatory regions of the A and B homologs in...

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PMID: 7547711
DOI: 10.1093/intimm/7.5.853

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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