Article
Tissue interleukin 1 and interleukin-1 receptor antagonist expression in enterocolitis in resistant and susceptible rats.
Gastroenterology - 1 Apr 1994
McCall R D, Haskill S, Zimmermann E M, Lund P K, Thompson R C, Sartor R B
Abstract excerpt
BACKGROUND/AIMS: Subserosal injection of purified group A streptococcal peptidoglycan-polysaccharide (PG-APS) induces chronic relapsing granulomatous enterocolitis and systemic inflammation in susceptible inbred Lewis rats but only transient intestinal injury in Buffalo and Fischer rats. Cecal in...
Topics
- Animals
- Cecum
- Enterocolitis
- Female
- Genetic Predisposition to Disease
- Interleukin-1
- Macrophages, Peritoneal
- Polysaccharides, Bacterial
- RNA, Messenger
- Rats
- Rats, Inbred BUF
- Rats, Inbred F344
- Rats, Inbred Lew
- Receptors, Interleukin-1
- Recombinant Proteins
- Streptococcus pyogenes