Article
Induced upregulation of IL-1, IL-1RA and IL-1R type I gene expression by Schwann cells.
Journal of neuroimmunology - 1 Apr 1997
Skundric D S, Bealmear B, Lisak R P
Abstract excerpt
We analyzed two distinct phenotypes of Schwann cells (SC), non-differentiated and differentiated, for their ability to produce IL-1alpha and IL-1beta, and to express message for IL-1 receptor antagonist (IL-IRA) and IL-1R type I, in vitro. SC were stimulated with: lipopolysaccharide (LPS), produc...
Topics
- Animals
- Dexamethasone
- Gene Expression Regulation
- Glucocorticoids
- In Situ Hybridization
- Interleukin-1
- Lipopolysaccharides
- Mice
- Phenotype
- Polymerase Chain Reaction
- Rats
- Rats, Sprague-Dawley
- Receptors, Interleukin-1
- Recombinant Proteins
- Schwann Cells
- Spleen
- Transcription, Genetic
