Glucocorticoid and/or glucocorticoid antagonist effects in inflammatory disease-susceptible Lewis rats and inflammatory disease-resistant Fischer rats.

doi:10.1210/endo.136.7.7789338

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Article

Glucocorticoid and/or glucocorticoid antagonist effects in inflammatory disease-susceptible Lewis rats and inflammatory disease-resistant Fischer rats.

Endocrinology - 1 Jul 1995

Karalis K, Crofford L, Wilder R L, Chrousos G P

Abstract excerpt

Lewis (LEW/N) and Fischer (F344) rats are inbred strains that respond antithetically to administration of several inflammatory stimuli. Thus, in response to streptococcal cell wall-derived peptidoglycan/polysaccharide, 6-week-old female Lewis rats develop acute and chronic polyarthritis, whereas...

Topics

Adrenal Glands
Animals
Arthritis
Carrageenan
Dexamethasone
Disease Susceptibility
Genetic Predisposition to Disease
Inflammation
Male
Mifepristone
Organ Size
Peptidoglycan

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polysaccharides, Bacterial

Rats

Rats, Inbred F344

Rats, Inbred Lew

Spleen

Streptococcus

Source

Open in PubMed

Identifiers

PMID: 7789338
DOI: 10.1210/endo.136.7.7789338

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7789338-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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