Kallikrein-kininogen system activation and bradykinin (B2) receptors in indomethacin induced enterocolitis in genetically susceptible Lewis rats.

doi:10.1136/gut.43.3.365

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Article

Kallikrein-kininogen system activation and bradykinin (B2) receptors in indomethacin induced enterocolitis in genetically susceptible Lewis rats.

Gut - 1 Sept 1998

Stadnicki A, Sartor R B, Janardham R, Stadnicka I, Adam A A, Blais C, Colman R W

Abstract excerpt

BACKGROUND: The plasma kallikrein-kinin (K-K) system is activated in acute and chronic relapsing intestinal inflammation induced in Lewis rats by intramural injection of exogenous bacterial components. AIMS: To determine whether this effect is model specific, K-K system activation was investigate...

Topics

Acute Disease
Animals
Anti-Inflammatory Agents, Non-Steroidal
Chronic Disease
Enterocolitis
Female
Genetic Predisposition to Disease
Immunohistochemistry
Indomethacin
Intestine, Small
Kallikrein-Kinin System

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Kininogen, High-Molecular-Weight

Kininogens

Prekallikrein

Rats

Rats, Inbred Lew

Receptor, Bradykinin B2

Receptors, Bradykinin

Source

Open in PubMed Open full text

Identifiers

PMID: 9863482
DOI: 10.1136/gut.43.3.365
PMCID: PMC1727239

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9863482-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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