Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Assessment of homology with the helical mimicry algorithm.

Biochimica et biophysica acta - 16 Feb 1994

Bositis C M, Craft N, Lew R A, Fowlie E J, Queenan J, Humphreys R E

Abstract excerpt

Homologies based on structural motifs characterize conserved structures and mechanisms of maintaining function. An algorithm was developed to quantitate homology among segments of two proteins based upon structural characteristics of an amphipathic alpha-helix. This helical mimicry algorithm scored homology among sequences of two proteins in terms of: (i) presence of Leu, Ile, Val, Phe, or Met in a longitudinal,...

Topics

Algorithms
Amino Acid Sequence
Animals
Chickens
Humans
Molecular Sequence Data
Muramidase
Mutation
Sequence Homology, Amino Acid

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8142458
DOI: 10.1016/0167-4838(94)90007-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8142458-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Assessment of homology with the helical mimicry algorithm.PMID 8142458Read ↗

Identification of potential molecular mimicry in pathogen-host interactionsSemantic proximity Read ↗

Amphiphilic α-helical potential: a putative folding motif adding few constraints to protein evolution.Semantic proximity Read ↗

mimicDetector: a pipeline for protein motif mimicry detection in host-pathogen systemsSemantic proximity Read ↗

Basic local alignment search tool.Semantic proximity Read ↗

Protein plasticity to the extreme: changing the topology of a 4-alpha-helical bundle with a single amino acid substitution.Semantic proximity Read ↗

Intramolecular mimicry. Identification and analysis of two cross-reactive T cell epitopes within a single protein.Semantic proximity Read ↗

Align-m--a new algorithm for multiple alignment of highly divergent sequences.Semantic proximity Read ↗

Database of homology-derived protein structures and the structural meaning of sequence alignment.Semantic proximity Read ↗

Use of homology domains in sequence similarity detection.Semantic proximity Read ↗

Structural basis of amino acid alpha helix propensity.Semantic proximity Read ↗

A similarity matrix-based hybrid algorithm for the contact map overlaps problem.Semantic proximity Read ↗

A combination of compositional index and genetic algorithm for predicting transmembrane helical segments.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.