Article
Database of homology-derived protein structures and the structural meaning of sequence alignment.
Proteins - 1 Jan 1991
Sander C, Schneider R
Abstract excerpt
The database of known protein three-dimensional structures can be significantly increased by the use of sequence homology, based on the following observations. (1) The database of known sequences, currently at more than 12,000 proteins, is two orders of magnitude larger than the database of known structures. (2) The currently most powerful method of predicting protein structures is model building by homology. (3)...
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