Article
A combination of compositional index and genetic algorithm for predicting transmembrane helical segments.
PloS one - 1 Jan 2011
Zaki Nazar, Bouktif Salah, Lazarova-Molnar Sanja
Abstract excerpt
UNLABELLED: Transmembrane helix (TMH) topology prediction is becoming a focal problem in bioinformatics because the structure of TM proteins is difficult to determine using experimental methods. Therefore, methods that can computationally predict the topology of helical membrane proteins are highly desirable. In this paper we introduce TMHindex, a method for detecting TMH segments using only the amino acid...
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