Article

mimicDetector: a pipeline for protein motif mimicry detection in host-pathogen systems

2025-05-05

Abstract excerpt

<h4>Motivation</h4> Molecular mimicry is a widespread strategy used by pathogens to evade the host immune system and manipulate other host cellular processes. Detecting these events—where pathogen proteins resemble host molecules—is challenging due to limitations in the sensitivity, specificity, and scalability of current bioinformatics tools. The challenges are pronounced when identifying subtle similarities in...

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Literature Corpus work: e7571065-e5d4-597d-a0cd-292deb5d97bb
DOI: 10.1101/2025.05.02.651971

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