Article
Use of homology domains in sequence similarity detection.
Methods in enzymology - 1 Jan 1990
Lawrence C B
Abstract excerpt
We have found the detection of homology domains using a nonlinear similarity score and the DD algorithm to be a useful approach for identifying similarity between sequences and evaluating potential homology. There are several reasons for the success of the method. (i) Homology domains are identified by a rigorous method that guarantees they will be locally optimal. (ii) The relative significance of different...
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