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Article

A similarity matrix-based hybrid algorithm for the contact map overlaps problem.

Computers in biology and medicine - 1 May 2011

Lu Hengyun, Yang Genke, Yeung Lam Fat

Abstract excerpt

This paper proposes a similarity matrix-based hybrid algorithm for the contact map overlap (CMO) problem in protein structure alignment. In this algorithm, Genetic Algorithm (GA) is used as a framework, in which the initial solutions are constructed with similarity matrix heuristic, and Extremal Optimization (EO) is embedded as a mutated operator. In this process, EO quickly approaches near-optimal solutions and...

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PMID: 21439563
DOI: 10.1016/j.compbiomed.2011.02.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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